Reconstructing IDF curves from daily rainfall records in data-scarce regions: A statistical method based on temporal disaggregation and gumbel modeling. [PDF]
PLoS OneMolino J +2 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Mapping Rare Disease Registries in Brazil: Situational Analysis and Proposal for National Unification. [PDF]
J Med SystBernardi FA +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Planck-scale effects on nucleon decay in minimal supersymmetric SU(5). [PDF]
Eur Phys J C Part FieldsEllis J +4 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Aesthetic sustainability: relational understanding in conservation research environments. [PDF]
Eur J Philos SciPoliseli L.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
SUPERGRAVITY AND COHOMOLOGY THEORY: PROGRESS AND PROBLEMS IN D = 5
, 1980 Erice Eps Unification Qcde +5 more
core
Oral hygiene and popular science: Paolo Mantegazza (1831-1910) and the question of sugar in dental caries. [PDF]
Br Dent JCompagnoni F, Riva MA.
europepmc +1 more source