Results 71 to 80 of about 393,847 (324)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Unification

open access: yes, 2015
This publication is comprised of two equations which are derived and extrapolated from a book that I created in 2015/2016: Probability, Quantum Mechanics, and Probability-Quanta. The latter consists of various thought experiments and postulates. I have included scans from the original book in an effort to demonstrate my work and in the hopes of ...
openaire   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Axion-Higgs Unification [PDF]

open access: yes, 2012
In theories with no fundamental scalars, one gauge group can become strong at a large scale Lambda and spontaneously break a global symmetry, producing the Higgs and the axion as composite pseudo-Nambu-Goldstone bosons.
A Arvanitaki   +29 more
core   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

b-tau Unification and neutrino masses in SU(5) extensions of the MSSM with radiative electroweak symmetry breaking

open access: yes, 1997
We make a complete analysis of the Yukawa coupling unification in SU(5) extensions of the MSSM in the framework of the radiative symmetry breaking scenario.
A. B. Lahanas   +42 more
core   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Simplification of International Trade Procedures as Result of a Customs Cooperation

open access: yesÈkonomika, Pedagogika i Pravo, 2016
In this article on the basis of result of the research conducted by the author importance of questions of simplification of procedures of trade for stimulation of growth and development of world economy is proved.
Aminat A. Bishenova
doaj  

Home - About - Disclaimer - Privacy