Results 91 to 100 of about 384,748 (295)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Preserving the Integrity of Organizations’ Quality Management System during Unification and Integration: Functional Approach

open access: yesВестник Кемеровского государственного университета. Серия: политические, социологические и экономические науки, 2023
The article addresses the problems of preserving the integrity of quality management systems during integration of educational organizations into a single educational complex.
Marina V. Sokolovskaya   +1 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Axion-Higgs Unification [PDF]

open access: yes
In theories with no fundamental scalars, one gauge group can become strong at a large scale Lambda and spontaneously break a global symmetry, producing the Higgs and the axion as composite pseudo-Nambu-Goldstone bosons.
A Arvanitaki   +29 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Topological Grand Unification [PDF]

open access: yes
We propose a new grand unification scenario for ensuring proton stability and triplet-doublet Higgs mass splitting with the help of topological symmetry and dynamics.Comment: 9 pages, version to appear in ...
Kawamura, Yoshiharu
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Ujednačavanje pomorskog prava i interesi Hrvatske

open access: yesPoredbeno Pomorsko Pravo, 2004
Republika Hrvatska, kao pomorska država, ima osobit interes pratiti unifikacijske težnje u uređenju pomorskopravnih odnosa. Hrvatska je poglavito dužna ratificirati i primjenjivati konvencije i dogovore iz područja sigurnosti plovidbe, njihove česte ...
Ivo Grabovac
doaj  

Aspectos institucionais da unificação das polícias no Brasil

open access: yesDados: Revista de Ciências Sociais, 2004
Dans cet article, on examine l'unification des polices militaire et civile brésiliennes en cherchant les références empiriques dans des études précédentes réalisées au sujet des polices des États de São Paulo, Minas Gerais et Rio de Janeiro.
Mateus Afonso Medeiros
doaj   +1 more source

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