Results 91 to 100 of about 99,447 (295)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
About Yugoslavia on the eve of its establishment: Nikola Pašić and British Prime Minister David Lloyd George about the future Yugoslav state on 15th October 1918 [PDF]
Sociološki Pregled, 2018 The study reviews the meeting of President of the Serbian Government Nikola Pašić and British Prime Minister David Lloyd George in London on 15th October 1918. On that occasion the two statesmen expressed their respective attitudes about the situation in
Sovilj Milan P.
doaj
Aspectos institucionais da unificação das polícias no Brasil
Dados: Revista de Ciências Sociais, 2004 Dans cet article, on examine l'unification des polices militaire et civile brésiliennes en cherchant les références empiriques dans des études précédentes réalisées au sujet des polices des États de São Paulo, Minas Gerais et Rio de Janeiro.
Mateus Afonso Medeiros
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
On the 'Burden' of German Unification: The Economic Consequences of Messrs. Waigel and Tietmeyer [PDF]
This paper investigates the causes of western Germany's remarkably poor performance since 1992. The paper challenges the view that the poor record of the nineties, particularly the marked deterioration in public finances since unification, might be ...
Jörg Bibow
core +2 more sources
MAXWELL’S THEORY WITH CHIRAL CURRENTS TEORÍA DE MAXWELL CON CORRIENTES QUIRALES
Ingeniare: Revista Chilena de Ingeniería, 2008 The energy and momentum content of an electromagnetic field can be expressed entirely in terms of the fields through the energy-momentum tensor with no mention of the sources creating the fields.
Héctor Torres-Silva
doaj
The limits of unification [PDF]
Proceedings of the 28th annual meeting on Association for Computational Linguistics -, 1990 Current complex-feature based grammars use a single procedure---unification---for a multitude of purposes, among them, enforcing formal agreement between purely syntactic features. This paper presents evidence from several natural languages that unification---variable-matching combined with variable substitution---is the wrong mechanism for effecting ...
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source