Results 101 to 110 of about 384,748 (295)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Lazy unification [PDF]

Proceedings of the 28th annual meeting on Association for Computational Linguistics -, 1990
Unification-based NL parsers that copy argument graphs to prevent their destruction suffer from inefficiency. Copying is the most expensive operation in such parsers, and several methods to reduce copying have been devised with varying degrees of success. Lazy Unification is presented here as a new, conceptually elegant solution that reduces copying by
openaire   +1 more source

Nucleon decay via dimension 6 operators in anomalous U(1)_A SUSY GUT

Nucleon lifetimes for various decay modes via dimension 6 operators are calculated in the anomalous $U(1)_A$ GUT scenario, in which the unification scale $\Lambda_u$ becomes smaller than the usual supersymmetric (SUSY) unification scale $\Lambda_G=2 ...
Maekawa, Nobuhiro, Muramatsu, Yu
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

SHARED AGENCY IN COMPLEX SETTINGS [PDF]

Filozofia i Nauka
The paper begins by identifying two opposing approaches to (shared) agency — the standard model and the dynamical model. Despite differences between them, both models essentially converge upon the belief that shared agency entails direct mutual influence
Anna Martin
doaj   +1 more source

Optimality in Goal-Dependent Analysis of Sharing

We face the problems of correctness, optimality and precision for the static analysis of logic programs, using the theory of abstract interpretation.
Amato, Amato, Apt, Cortesi, Cousot, FRANCESCA SCOZZARI, Furukawa, GIANLUCA AMATO, Hans, Henkin, King, King, Le Charlier, Lloyd, Muthukumar, Palamidessi, Søndergaard   +16 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

MAXWELL’S THEORY WITH CHIRAL CURRENTS TEORÍA DE MAXWELL CON CORRIENTES QUIRALES

Ingeniare: Revista Chilena de Ingeniería, 2008
The energy and momentum content of an electromagnetic field can be expressed entirely in terms of the fields through the energy-momentum tensor with no mention of the sources creating the fields.
Héctor Torres-Silva
doaj