Results 71 to 80 of about 99,447 (295)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Emergent Braided Matter of Quantum Geometry
Symmetry, Integrability and Geometry: Methods and Applications, 2012 We review and present a few new results of the program of emergent matter as braid excitations of quantum geometry that is represented by braided ribbon networks.
Sundance Bilson-Thompson +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
"Save the human race, punch a Moonie in the face" : The Unification Church from Cult to Corporation [PDF]
, 2012 From the 60's to the early 80's numerous religious and social groups arose due to the political climate that permeated the entire world. One such group that gained notoriety but since has fallen into America's distant memory is the Unification Movement ...
Wilkinson, Amanda A.
core
Tyragetia, 2017 Romania's entry into the First World War was preceded by fierce diplomatic battles between the two warring parties – the Entente and the Triple Alliance – regarding its involvement in the conflict on one side or the other.
Anatolie Povestca
doaj
Theoretical Computer Science, 1988 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Deepak Kapur +3 more
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Proceedings of the 28th annual meeting on Association for Computational Linguistics -, 1990 Unification-based NL parsers that copy argument graphs to prevent their destruction suffer from inefficiency. Copying is the most expensive operation in such parsers, and several methods to reduce copying have been devised with varying degrees of success. Lazy Unification is presented here as a new, conceptually elegant solution that reduces copying by
openaire +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source