Results 61 to 70 of about 23,694 (255)

Analisis dan Desain Sistem Sertifikasi Padi Digital sebagai Sarana Pemasaran serta Peningkatan Adopsi Benih

open access: yesIndustria: Jurnal Teknologi dan Manajemen Agroindustri, 2018
Abstrak Penggunaan varietas padi unggul adalah inovasi teknologi yang mudah diadopsi untuk peningkatan produktivitas padi. Tanpa program benih bersubsidi, banyak petani tidak menggunakan benih padi berkualitas/bersertifikat karena tidak tersedianya ...
Yogi Purna Rahardjo   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Toward Unified Chinese Multi-Dialectal Speech Recognition via Pinyin Intermediate Representation

open access: yesIEEE Access
Multi-dialect speech recognition is essential for the widespread adoption of intelligent interactive systems and the preservation of dialectal language resources.
Junjie Cheng, Xiaorong Wu
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Analysis and Design of Restaurant Information System using Unified Modeling Language

open access: yesSISFORMA, 2019
This research was done with the aim of facilitating the Admin access to process raw material inventory data which outlets and warehouses are located in different cities.
Agustinus Fritz Wijaya   +1 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Pemodelan Sistem Penelusuran Daging Sapi Potong Menggunakan Metode Unified Modeling Language

open access: yesJurnal Teknologi dan Industri Pertanian Indonesia, 2018
Isu mengenai beredarnya produk daging sapi yang dicampur daging babi celeng semakin marak akhir ini. Pemicu utama adalah ketidakmampuan pedagang membeli harga daging sapi yang mahal sehingga mendatangkan keuntungan yang sedikit.
Paramita Setyaningrum
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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