Results 71 to 80 of about 24,037 (257)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

THE OBJECTUAL DATABASE DESIGN FOR A VIRTUAL STORE [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
Nowadays, the most systems on the Internet are using databases. These databases are relational and normalized. Although the tables of the relational model itself does not have a behaviour in context object, though the diagrams uses different methods.
Avornicului Constantin   +2 more
doaj  

Sistem Aplikasi Pencarian Lokasi Parkir Terdekat Menggunakan Location Based Service Berbasis Android

open access: yesKomputika, 2017
Tujuan dari penelitian ini adalah membuat aplikasi pencarian parker terdekat sehingga dapat mempermudah pengguana parker dalam mencari tempat parker yang terdekat dan yang kosong.
Sri Nurhayati, Egi Nur Ilmi
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Technique of analyzing device drivers of embedded linux system using UML

open access: yesTongxin xuebao, 2012
A method to model and analyze the device drivers in embedded Linux system using UML was proposed.By using UML modeling method,the dependencies among the device driver components and the focus of the device driver development are clarified.On this basis ...
Liang MA, Li LI, Su-bin SHEN
doaj   +2 more sources

Sistema Informático para Gestionar Información del Claustro de Programas Académicos de la Educación Superior en Cuba

open access: yesSociedad & Tecnología, 2019
El Sistema de Evaluación y Acreditación de la Educación Superior establecido por la Junta de Acreditación Nacional en Cuba evalúa para los diferentes programas académicos cinco variables claves: pertinencia e impacto social, claustro, estudiantes ...
Alfredo Rafael Espinosa Palenque   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

SISTEM INFORMASI INVENTORY BERBASIS DOTNET ( STUDI KASUS TOKO SINGAPORE SHOES TEMBILAHAN)

open access: yesSistemasi: Jurnal Sistem Informasi, 2018
Singapore Shoes is a store that sells shoes, handbags, wallets and other accessories. Inventory system is a very important part in the operator of an enterprise, manufacturing inventory system affects the level of income and corporate earnings. Therefore,
Usman Usman, Zainuddin Zainuddin
doaj  

Pembuatan Aplikasi Portal Akademik Berbasis Mobile (Studi Kasus: D3 Manajemen Informatika FMIPA Universitas Riau)

open access: yesDigital Zone: Jurnal Teknologi Informasi dan Komunikasi, 2017
Abstrak- Penelitian ini membahas tentang aplikasi portal akademik berbasis mobile, studi kasus pada D3 Manajemen Informatika Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riau.
Sukamto Sukamto   +3 more
doaj   +1 more source

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