Results 91 to 100 of about 511 (254)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A Review on Development in Unified Power Quality Conditioner

open access: yesJournal of Electrical Systems
Power quality issues such as voltage sags, swells, harmonics, and interruptions are significant concerns in modern electrical networks, affecting the reliability and efficiency of power supply to consumers. These issues can lead to equipment malfunction, increased downtime, and financial losses for industries.
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

A Novel Three-Phase Multiobjective Unified Power Quality Conditioner

open access: yesIEEE Transactions on Industrial Electronics
The decarbonization of the economy and the increasing integration of renewable energy sources into the generation mix are bringing new challenges, requiring novel technological solutions in the topic of smart grids, which include smart transformers and energy storage systems.
Vítor Monteiro   +6 more
openaire   +3 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Application of a three‐phase unified power quality conditioner in a microgrid

open access: yesIET Smart Grid
In power distribution systems, common issues such as voltage fluctuations, voltage instability, current harmonics, and power imbalances often arise, negatively impacting the stability and power quality (PQ) of the power system.
Tsung‐Hsun Wu   +2 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

INTEGRATION OF ARTIFICIAL INTELLIGENCE CONTROL TO THE UNIFIED POWER QUALITY CONDITIONER

open access: yesInternational Journal of Research in Engineering and Technology, 2012
Modernization of the Industrial world is completely accompanied with growing power demands. It is very necessary to utilize the available power efficiently with as much less issues as possible rather than focusing on the excessive generation to meet the demand.
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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