Results 61 to 70 of about 4,796,670 (284)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Specific requirements that significantly affect the design of military uniform [PDF]
This paper presents the importance of the uniform for conduct of combat operations, as well as the requirements that it must meet. It is based on uniform studies, reports by certified institutions that have tested the uniform, based on previous analyses ...
Nikolić Srboljub +2 more
doaj +1 more source
Although increasingly disputed, the white coat uniform is ubiquitous in geriatric care, which may reflect a phenomenon called medicalisation of ageing. This narrative review is the first attempt at integrating several theoretical approaches, such as the “
Coline Crutzen, Stéphane Adam
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Laser cleaning of textile artifacts with metal threads: Process parameter optimization [PDF]
This paper presents the results of the laser cleaning effects on textile samples with corroded metallic threads. In many museum collections, there are textile exhibits like uniforms, national costumes, flags and home textile, embroidered with metallic ...
Ristić Slavica +4 more
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Uniform-Velocity Spacetime Crystals
We perform a comprehensive analysis of uniform-velocity bilayer spacetime crystals, combining concepts of conventional photonic crystallography and special relativity. Given that a spacetime crystal consists of a sequence of spacetime discontinuities, we
Caloz, Christophe +4 more
core +1 more source
Uniformization of quasi-uniform spaces [PDF]
This paper considers the question of when a quasi-uniform space has a compatible uniform structure. Typical of the sufficient conditions provided is the result that a quasi-uniform space whose conjugate topology is compact and R0 is uniformizable.
Raghavan, T. G., Reilly, I. L.
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Examining the role of nickel and NiTi nanoparticles promoting inflammation and angiogenesis
Nickel titanium (NiTi, or Nitinol) alloy is used in several biomedical applications, including cardiac, peripheral vascular, and fallopian tube stents.
Anup K. Srivastava +5 more
doaj +1 more source

