Results 81 to 90 of about 4,796,670 (284)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The uniform electron gas

open access: yes, 2016
The uniform electron gas or UEG (also known as jellium) is one of the most fundamental models in condensed-matter physics and the cornerstone of the most popular approximation --- the local-density approximation --- within density-functional theory.
Gill, Peter M. W.   +1 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Star-Uniform Graphs

open access: yesGraphs and Combinatorics, 2010
A {\it star-factor} of a graph $G$ is a spanning subgraph of $G$ such that each of its component is a star. Clearly, every graph without isolated vertices has a star factor. A graph $G$ is called {\it star-uniform} if all star-factors of $G$ have the same number of components.
Kano, Mikio, Wu, Yunjian, Yu, Qinglin
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Genuinely multipartite entangled states and orthogonal arrays

open access: yes, 2014
A pure quantum state of N subsystems with d levels each is called k-multipartite maximally entangled state, written k-uniform, if all its reductions to k qudits are maximally mixed.
Goyeneche, Dardo, Zyczkowski, Karol
core   +1 more source

Numerical Schottky Uniformizations

open access: yesGeometriae Dedicata, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hidalgo, RA, Figueroa, J
openaire   +5 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Attributes of power in top wears of guardian spirits of the Northern Khanty in the XX — beginning of the XXI century

open access: yesВестник археологии, антропологии и этнографии, 2017
The article is dedicated to a study of top wears of guardian spirits. It is based on the materials obtained du-ring ethnographic expeditions to the areas of residence of a northern group of the Khanty, and on the items from a museum collection.
Bogordayeva A.A.
doaj   +1 more source

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