Results 151 to 160 of about 132,438 (286)

A Data‐Driven Redefinition of Early Relapse in Pediatric T Cell Acute Lymphoblastic Leukemia: Evidence for Progression of Disease 15 Months

open access: yesMed Research, EarlyView.
Data‐driven redefinition of early relapse in pediatric T‐ALL using hazard modeling, cumulative incidence, and time‐dependent HR across 1533 patients in three independent cohorts identifies 15 months as the optimal threshold. By integrating temporal risk metrics and external validation, this study provides evidence for POD ≤ 15 months as a data‐driven ...
Na Zhang   +6 more
wiley   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés   +2 more
wiley   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang   +5 more
wiley   +1 more source

Exponential Stability of Higher Order Fractional Neutral Stochastic Differential Equation Via Integral Contractors

open access: yesMathematical Methods in the Applied Sciences, Volume 48, Issue 6, Page 6425-6446, April 2025.
ABSTRACT The well‐posedness results for mild solutions to the fractional neutral stochastic differential system with Rosenblatt process with Hurst index Ĥ∈12,1$$ \hat{H}\in \left(\frac{1}{2},1\right) $$ is discussed in this article. To demonstrate the results, the concept of bounded integral contractors is combined with the stochastic result and ...
Dimplekumar N. Chalishajar   +3 more
wiley   +1 more source

Mathematical Analysis and Simulations of a Cancer Model With Interleukins and Delayed Immunotherapy

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT A new system of delayed differential equations for tumor‐immune system interactions is proposed and studied. The system describes the interactions between tumor cells and the immune system at the most aggressive phase of cancer, where tumor cells have developed mechanisms from earlier stages to evade immune responses.
Laid Boudjellal   +2 more
wiley   +1 more source

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