Results 51 to 60 of about 1,127,269 (277)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Continuous dependence and fixed points for some multivalued operators
Journal of Numerical Analysis and Approximation Theory, 1997 In this paper we extend the notion of \(I^0\)-continuity and uniform \(I^0\)-continuity from [2] to set-valued operators. For families of such operators we prove (semi)continuity of the fixed point sets.
Eduard Kirr, Adrian Petrușel
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The uniform continuity of continuous functions on a topological space [PDF]
Proceedings of the American Mathematical Society, 1963 Two questions motivate. this study: To what extent is it possible to restructure the common domain of a family of continuous functions so that they all become uniformly continuous? When can a group of homeomorphisms of a completely regular space be interpreted as a topological transformation group?
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Journal of Inequalities and Applications, 2020 This paper concerns the long term behavior of the stochastic two-dimensional g-Navier–Stokes equations with additive noise defined on a sequence of expanding domains, where the ultimate domain is unbounded and of Poincaré type.
Fuzhi Li, Dongmei Xu, Lianbing She
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Coherence Spaces and Uniform Continuity [PDF]
, 2017 In this paper, we consider a model of classical linear logic based on coherence spaces endowed with a notion of totality. If we restrict ourselves to total objects, each coherence space can be regarded as a uniform space and each linear map as a uniformly continuous function.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
MathematicsThis paper investigates the uniform continuity and strong continuity of the semigroups of the fractional integral operators of power functions. Using the Krasnoselskii’s fixed-point theorem, we have studied the non-local problem related to fractional ...
Zhengzhi Lu
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