Results 71 to 80 of about 115,275 (294)

Prediction of Random Vibration Fatigue Damage Using Isogeometric Modelling

open access: yesComputer Assisted Methods in Engineering and Science, 2022
The finite element analysis (FEA) method is indispensable in simulation technology, as it can help engineers predict results to avoid the cost of experimental testing.
Shubiao Wang   +3 more
doaj   +1 more source

Uniform Random Number Generation [PDF]

open access: yes, 2004
This chapter covers the basic design principles and methods for uniform random number generators used in simulation. We also briefly mention the connections between these methods and those used to construct highly-uniform point sets for quasi-Monte Carlo
Pierre L'Ecuyer
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Harvesting Entropy for Random Number Generation for Internet of Things Constrained Devices Using On-Board Sensors

open access: yesSensors, 2015
Entropy in computer security is associated with the unpredictability of a source of randomness. The random source with high entropy tends to achieve a uniform distribution of random values.
Marcin Piotr Pawlowski   +2 more
doaj   +1 more source

Neural network-based regression for heat transfer and fluid flow over in-line cylinder arrays with random pitch distances at low Reynolds number

open access: yesEngineering Applications of Computational Fluid Mechanics, 2023
Finding an arrangement, leading to a higher heat transfer and lower pressure drop, is crucial in the design of heat exchangers. Previous studies have primarily focused on regular arrangements with uniform pitch distances, which lack applicability to ...
Geunhyeok Choi   +2 more
doaj   +1 more source

High performance FPGA implementation of the mersenne twister [PDF]

open access: yes, 2008
Efficient generation of random and pseudorandom sequences is of great importance to a number of applications [4]. In this paper, an efficient implementation of the Mersenne Twister is presented. The proposed architecture has the smallest footprint of all
Shrutisagar Chandrasekaran   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Generation of Focal Patterns With Uniform Intensity Distribution From Speckle by Hadamard-Genetic Algorithm

open access: yesIEEE Photonics Journal, 2021
When a coherent beam transmits through a scattering medium, a random intensity distribution known as speckle is generated. Generally, such speckles can be modulated by feedback-based wavefront shaping, as exemplified by the generation of a bright focal ...
Haoran Li   +6 more
doaj   +1 more source

Close to Uniform Prime Number Generation With Fewer Random Bits [PDF]

open access: yes, 2011
In this paper we analyze a simple method for generating prime numbers with fewer random bits. Assuming the Extended Riemann Hypothesis, we can prove that our method generates primes according to a distribution that can be made arbitrarily close to ...
Pierre-Alain Fouque, Mehdi Tibouchi
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy