Results 61 to 70 of about 4,846,870 (280)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Some conditions under which a uniform space is fine [PDF]
, 1993 summary:Let $X$ be a uniform space of uniform weight $\mu$. It is shown that if every open covering, of power at most $\mu$, is uniform, then $X$ is fine.
Marconi, Umberto
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Stability of common fixed points in uniform spaces
Fixed Point Theory and Applications, 2011 Stability results for a pair of sequences of mappings and their common fixed points in a Hausdorff uniform space using certain new notions of convergence are proved. The results obtained herein extend and unify several known results.
Singh Shyam +2 more
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Uniform graph embedding into metric spaces [PDF]
Компьютерные исследования и моделирование, 2012 The task of embedding an infinity countable graph into continuous metric space is considered. The concept of uniform embedding having no accumulation point in a set of vertex images and having all graph edge images of a limited length is introduced ...
A. V. Koganov
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, 2022 The U.S. Congress passed the National Defense Act in June 1916 which provided for the formation of the Reserve Officers' Training Corps (ROTC). The first unit formed at Georgia Tech in March 1918.
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2006 The main purpose of this paper is to introduce a new structure that is a fuzzy TL-uniform space. We show that our structure generates a fuzzy topological space, precisely, a fuzzy T-locality space.
Khaled A. Hashem, Nehad N. Morsi
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source