Results 21 to 30 of about 78,630 (216)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Topology of Quantum Algorithms
, 2013 We use a categorical topological semantics to examine the Deutsch-Jozsa, hidden subgroup and single-shot Grover algorithms. This reveals important structures hidden by conventional algebraic presentations, and allows novel proofs of correctness via local
Vicary, Jamie
core +1 more source
, 2000 We introduce the notion of a topological symmetry as a quantum mechanical symmetry involving a certain topological invariant. We obtain the underlying algebraic structure of the Z_2-graded uniform topological symmetries of type (1,1) and (2,1).
A. MOSTAFAZADEH +2 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Approximating invariant densities of metastable systems
, 2009 We consider a piecewise smooth expanding map of the interval possessing two invariant subsets of positive Lebesgue measure and exactly two ergodic absolutely continuous invariant probability measures (ACIMs).
Blank +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Bulletin of Belgorod State Technological University named after. V. G. Shukhov, 2020 The article discusses the main aspects of the architect's work with the normative documents used in technical regulation in the construction of buildings of educational institutions in the Russian Federation and the Belgorod region. The analysis of the current standardization system confirmed the relevance of the studied problem, which is determined by
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source