Results 51 to 60 of about 217,028 (268)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Optical Design of an LED Lighting Source for Fluorescence Microscopes

open access: yesApplied Sciences, 2019
In this study, we reveal an LED light source model applied in fluorescence microscopes. This optical model is composed of a confocal total internal reflection lens array system (CTLAS) with a nine-LED array.
Tai-Chih Kuo   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Improving Air Distribution Within Lettuce Plant Canopy by Employing Double-Channel Ventilation Cultivation System: Simulation and Experiment Study

open access: yesAgronomy
In greenhouse and plant factory production, improper design of the ventilation system and increasing scales will lead to a stagnant airflow zone, which could inhibit plant growth and induce physiological disease, such as tipburn.
Yihan Zhang   +3 more
doaj   +1 more source

Refined Test and Evaluation Method of Side Viewing Angle of LED Display Module

open access: yesApplied Sciences, 2022
In order to classify light-emitting diode (LED) display units with a specific luminous direction and improve the uniformity of the display screen, this paper proposes a classification method for the basic component of the LED display, i.e., the display ...
Shuo Huang   +4 more
doaj   +1 more source

Uniform Space [PDF]

open access: yesFormalized Mathematics, 2016
Abstract In this article, we formalize in Mizar [1] the notion of uniform space introduced by André Weil using the concepts of entourages [2]. We present some results between uniform space and pseudo metric space. We introduce the concepts of left-uniformity and right-uniformity of a topological group. Next,
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effects of Perforation Location in Gas Diffusion Layers on Electrochemical Characteristics of Proton Exchange Membrane Fuel Cells

open access: yesApplied Sciences
Water management is a critical issue for improving both the performance and durability of proton exchange membrane fuel cells (PEMFCs). A gas diffusion layer (GDL), as a porous medium, plays a key role in liquid water removal, reactant supply, and ...
Dong Kun Song   +4 more
doaj   +1 more source

Distribuição da carga hidráulica em linhas de derivação otimizadas por programação linear Hydraulic head distribution on manifolds optimized by linear programming

open access: yesEngenharia Agrícola, 2006
A existência de diferentes combinações de uniformidade de emissão na unidade operacional com a declividade do terreno favorece a ocorrência de várias possibilidades de configurações no sistema de irrigação, por conseguinte de diferentes custos de ...
João C. C. Saad   +1 more
doaj   +1 more source

Study on the dose uniformity of multi-channel parallel diode

open access: yesFushe yanjiu yu fushe gongyi xuebao, 2023
The multi-channel parallel diode structure is effective in obtaining X-ray with low energy, large area coverage, and high dose rate in laboratory conditions.
LI Jinxi   +4 more
doaj   +1 more source

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