Results 81 to 90 of about 379,419 (302)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

PRODUCER RETURNS FROM COTTON STRENGTH AND UNIFORMITY: AN HEDONIC PRICE APPROACH [PDF]

open access: yes
Implicit (hedonic) producer prices for fiber strength uniformity were estimated for the southwest U.S. cotton market using seemingly unrelated regression and market sales data from 1983/84 and 1984/85, Fiber strength and length uniformity had significant
Neeper, Jarral T., Ethridge, Don E.
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Formation of uniform magnetic flux distribution for NMR magnets using HTS bulk magnets activated by pulsed-field magnetization

open access: yesMaterials Research Express, 2020
Nuclear magnetic resonance (NMR) magnets generally need an extremely uniform magnetic field in the space where the specimens will be placed. Although high temperature superconducting bulk magnets can obtain an intense magnetic field of more than 3 T, the
T Oka   +10 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The image generating algorithms of micro-pits with direction-uniformity distribution of YAG laser texturing roll based on square partial scrambling

open access: yes, 2012
Two image generating algorithms based on square partial scrambling are raised to implement micro-pits with approximate uniformity distribution of YAG laser texturing roll. Micro-pits can be uniformly distributed to ensure the area-uniformity of the micro-
王红才   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Feature Uniformity for FPLs.

open access: yes, 2014
Feature Uniformity for FPLs.
Sher Afzal Khan (526844)   +4 more
core   +1 more source

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