Results 41 to 50 of about 3,082,536 (295)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Abstract and Applied Analysis, 2012 Let {𝑡𝑛}⊂(0,1) be such that 𝑡𝑛→1 as 𝑛→∞, let 𝛼 and 𝛽 be two positive numbers such that 𝛼+𝛽=1, and let 𝑓 be a contraction. If 𝑇 be a continuous asymptotically pseudocontractive self-mapping of a nonempty bounded closed convex subset 𝐾 of a real reflexive ...
Xionghua Wu +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Journal of Inequalities and Applications, 2010 Motivated and inspired by the recent works on implicit iteration methods, we prove necessary and sufficient conditions for strong convergence of the eventually implicit iteration methods with errors to a common fixed point of a discrete family which is ...
Tae-Hwa Kim, Kui-Yeon Kim
doaj +2 more sources
An Iterative Algorithm on Approximating Fixed Points of Pseudocontractive Mappings
Journal of Applied Mathematics, 2012 Let E be a real reflexive Banach space with a uniformly Gâteaux differentiable norm. Let K be a nonempty bounded closed convex subset of E, and every nonempty closed convex bounded subset of K has the fixed point property for non-expansive self-mappings.
Youli Yu
doaj +1 more source
A new cardinal function on topological spaces
Applied General Topology, 2017 Using neighbourhood assignments, we introduce and study a new cardinal function, namely GCI(X), for every topological space X. We shall mainly investigate the spaces X with finite GCI(X).
Dewi Kartika Sari, Dongsheng Zhao
doaj +1 more source
Absolutely continuous invariant measures for random non-uniformly expanding maps [PDF]
Mathematische Zeitschrift, 2014 We prove existence of (at most denumerable many) absolutely continuous invariant probability measures for random one-dimensional dynamical systems with asymptotic expansion. If the rate of expansion (Lyapunov exponents) is bounded away from zero, we obtain finitely many ergodic absolutely continuous invariant probability measures, describing the ...
Araujo, Vitor, Solano, Javier
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
On closed mappings uniform spaces
Қарағанды университетінің хабаршысы. Математика сериясы, 2015 Uniform spaces are an important class of spaces in general topology. The purpose of the study is to prove new theorems concerning the properties of uniform spaces.
A.I. Chanbaeva
doaj
Journal of Applied Mathematics, 2012 We prove the existence of solutions for third-order nonconvex state-dependent sweeping process with unbounded perturbations of the form: -A(x(3)(t))∈N(K(t,ẋ(t)); A(ẍ(t)))+F(t,x(t),ẋ(t),ẍ(t))+G(x(t),ẋ(t),ẍ(t)) a.e. [0,T], A(ẍ(t))∈K(t,ẋ(t)),
M. Bounkhel, B. Al-Senan
doaj +1 more source