Results 91 to 100 of about 515,577 (303)

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

open access: yesAdvanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang   +8 more
wiley   +1 more source

Unilateral Emissions Abatement: An Experiment [PDF]

open access: yes
According to the model of HOEL (1991), a unilateral emissions abatement of a global pollutant leads to lower aggregated emissions in a game with a simultaneous decision protocol.
Bodo Sturm, Joachim Weimann
core  

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Comparing the efficacy and safety of unilateral versus bilateral spinal anesthesia: a meta-analysis and systematic review

open access: yesAnnals of Medicine
Background Unilateral spinal anesthesia has gained increasing attention in recent years. Emerging evidence suggests that it provides comparable analgesia to conventional bilateral spinal anesthesia while reducing adverse effects, and its efficacy and ...
Ji-Xiang Wan   +5 more
doaj   +1 more source

Unilateral rectus sternalis muscle - a case report

open access: yesNational Journal of Clinical Anatomy, 2016
Rectus sternalis muscle, either unilateral or bilateral is an uncommon anatomical variant among the anterior chest wall muscles. During the routine dissection as a part of undergraduate medical teaching in the department of Anatomy, a unilateral rectus ...
Smitha S Nair   +3 more
doaj   +1 more source

UNILATERAL TEMPERATURES.

open access: yesThe Lancet, 1891
n ...
openaire   +1 more source

On unilateral divorce and the "selection of marriages" hypothesis [PDF]

open access: yes
This paper revisits the issue of the unilateral divorce law, taking into account that: 1/ the decisions to engage in marriage and then to divorce or to stay married are fundamentally sequential decisions; 2/ household consumption has a large joint ...
Langlais, Eric
core  

Mirror illusion reduces motor cortical inhibition in the ipsilateral primary motor cortex during forceful unilateral muscle contractions [PDF]

open access: yes, 2015
Forceful, unilateral contractions modulate corticomotor paths targeting the resting, contralateral hand. However, it is unknown if mirror-viewing of a slowly moving but forcefully contracting hand would additionally affect these paths.
Hortobágyi, Tibor   +5 more
core   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

The effect of exercise complexity on trunk muscle activation and perceived exertion during body-weight training in recreationally trained adults

open access: yesFrontiers in Sports and Active Living
IntroductionThe aim of the present study was to investigate the acute effects of varying exercise complexity on trunk muscle activity in recreationally trained adults during seven trunk-specific body-weight (BW) exercises.MethodsTwenty-eight participants
Vidar Andersen   +8 more
doaj   +1 more source

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