Results 111 to 120 of about 462,231 (314)

Molecular characterization of drug-resistant and drug-sensitive Aspergillus isolates causing infectious keratitis

Indian Journal of Ophthalmology, 2011
Purpose: To study the susceptibilities of Aspergillus species against amphotericin B in infectious keratitis and to find out if drug resistance had any association with the molecular characteristics of the fungi.
Niranjan Nayak, Gita Satpathy, Sujata Prasad, Jeewan S Titiyal, R M Pandey, Rasik B Vajpayee   +5 more
doaj   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

On unilateral divorce and the "selection of marriages" hypothesis [PDF]

This paper revisits the issue of the unilateral divorce law, taking into account that: 1/ the decisions to engage in marriage and then to divorce or to stay married are fundamentally sequential decisions; 2/ household consumption has a large joint ...
Langlais, Eric
core   +1 more source

Comparisons of unilateral and bilateral cochlear implantation for children: spatial listening skills and quality of life [PDF]

, 2010
Recently, controversy in the care of severely-profoundly deaf children has centred on whether they should be provided with bilateral cochlear implants (two implants, one in each ear) rather than a unilateral cochlear implant (one implant in one ear ...
Lovett, Rosemary Elizabeth Susan
core  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Unilateral hippocampal sparing during whole brain radiotherapy for multiple brain metastases: narrative and critical review

Frontiers in Oncology
BackgroundThe landscape of brain metastases radiotherapy is evolving, with a shift away from whole-brain radiotherapy (WBRT) toward targeted stereotactic approaches aimed at preserving neurocognitive functions and maintaining overall quality of life. For
Petr Pospisil, Petr Pospisil, Ludmila Hynkova, Ludmila Hynkova, Lucie Hnidakova, Lucie Hnidakova, Jana Maistryszinova, Jana Maistryszinova, Pavel Slampa, Pavel Slampa, Tomas Kazda, Tomas Kazda   +11 more
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Isolated unilateral disk edema [PDF]

, 2011
Paul VarnerJohn J Pershing VAMC, Poplar Bluff, MO, USAAbstract: Isolated unilateral disk edema is a familiar clinical presentation with myriad associations.
Varner P
core  

Multimodal Imaging in a Case of Unilateral Fovea Hypoplasia

Delhi Journal of Ophthalmology
Fovea hypoplasia (FH) is a rare, bilateral condition described as the anatomical absence of the foveal pit. FH can be diagnosed and classified with optical coherence tomography (OCT) and other imaging modalities such as fundus autofluorescence and OCT ...
Preet Kanwar Singh Sodhi, Shivangi Singh
doaj   +1 more source