Results 71 to 80 of about 1,917,813 (302)
The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Advanced Science, EarlyView.Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
Advanced Science, EarlyView.Benzotriazole (BTA) regulates Zn reduction kinetics and suppresses galvanic corrosion, simultaneously mitigating Zn pulverization during cycling and self‐corrosion during storage, thereby enabling lean Zn anodes with enhanced cycling stability and extended calendar life.
Jing Xu +7 more
wiley +1 more source
Multigrid Methods for Unilateral Contact Problems with Friction [PDF]
, 2007 In this paper, multigrid methods are tested on unilateral problems with friction. An optimal strategy is presented and efficiency of the solver is discussed on several examples.
Lebon, Frédéric +2 more
openaire +2 more sources
Fatigue analysis of catenary contact wires for high speed trains [PDF]
, 2011 The fatigue fracture is one of the most critical failures which may occur on the high speed network because it is undetectable and it has a huge impact on traffic disruption.
MAITOURNAM, Habibou +4 more
core
Advanced Science, EarlyView.An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai +10 more
wiley +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Advanced Science, EarlyView.AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang +19 more
wiley +1 more source
Specular microscopy of unilateral hard contact lens wearers
Indian Journal of Ophthalmology, 1989 The effects of long term wear of PMMA contact lenses on the corneal endothelium used on a daily wear basis were determined by examining 8 patients who had been prescribed lenses in one eye only. The patients excluded unilateral aphakes. It was found that
Dada Vijay, Jain Arun, Mehta Manoj
doaj
A quasistatic unilateral contact problem with friction for nonlinear elastic materials
Mathematical Modelling and Analysis, 2007 The aim of this paper is to prove the existence of a solution to the quasistatic unilateral contact problem with a modified version of Coulomb's law of dry friction for nonlinear elastic materials. We derive a variational incremental problem which admits
Arezki Touzaline, Djamel Eddine Teniou
doaj +1 more source
Optimization problems for elastic contact models with unilateral constraints
, 2018 Optimization problems for elastic contact models with unilateral ...
Mircea Sofonea +5 more
core +1 more source