Results 91 to 100 of about 5,723,247 (300)

Retrograde Nail vs Distal Femoral Plate in Management of Distal Femur Fracture

open access: yesArcades of Medicine
Background Fractures of distal femur are responsible for about 3–6% of femur fractures. There are variable fixation methods of distal fractures of femur with different outcomes, among which are retrograde nailing and distal femoral plate.
ibrahim reda   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Decision on the Use of Spanish Within The African Union [PDF]

open access: yes, 2019
Decision on the Introduction of Spanish within the African Union and the relevant provisions of the Rules of Procedure of the Assembly in this ...
African Union
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

SEVENTH REPORT OF THE AFRICAN UNION ADVISORY BOARD ON CORRUPTION TO THE EXECUTIVE COUNCIL OF THE AFRICAN UNION [PDF]

open access: yes, 2016
The African Union Advisory Board on Corruption (AUABC) was established in accordance with the provisions of article 22 (5) (a) of the African Union Convention on Preventing and Combating Corruption (AUCPCC).
AFRICAN UNION
core   +1 more source

The fighters for the unification in the collections of the National Museum of History of Moldova: Constantin Stere

open access: yesTyragetia, 2018
Constantine Stere, a complex personality, a lawyer, a university lecturer, a newspaper founder, writer and politician, who was called “the great apostle of unification”, was the embodiment of the national ideal of unification of Bessarabia with Romania ...
Vera Stavilă
doaj  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Mise à jour de la fiche signalétique de l’Écosse

open access: yesRevue Française de Civilisation Britannique, 2019
The theme of updating Scotland’s documents developed in this article is centred on three points: the names and portraits of the nation, how valid the state of the union with England can be today (when compared to how powerful the idea of marriage was in ...
Jean Berton
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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