Results 81 to 90 of about 5,203,932 (313)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Activity Report of African Union Commission on International Law (AUCIL) [PDF]
, 2019 Executive Council Thirty-Fourth Ordinary Session 7 – 8 February 2019 Addis Ababa, EthiopiaAssembly of the Union Thirty-Second Ordinary Session 10 - 11 February 2019 Addis Ababa, EthiopiaThe activity report of the African Union Commission on International
African Union
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CSR behavior’s configurations in a post-revolutionary context
Cogent Business & ManagementThis study was conducted in Tunisia in the post-revolution context. It is based on the corporate social responsibility (CSR) analysis framework. Its objective is to classify the CSR behaviors of the two companies according to this analytical framework by
Amel Bouderbala, Adnane Malek
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Draft African union budget for the year 2009 [PDF]
, 2009 Assembly of the African union twelfth ordinary session 1 – 3 February 2009 Addis Ababa ...
Africa union
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Retrograde Nail vs Distal Femoral Plate in Management of Distal Femur Fracture
Arcades of MedicineBackground Fractures of distal femur are responsible for about 3–6% of femur fractures. There are variable fixation methods of distal fractures of femur with different outcomes, among which are retrograde nailing and distal femoral plate.
ibrahim reda +3 more
doaj +1 more source
Defect Detection Test and Mechanical-magnetic Coupling Simulation of High-pressure Union
Shiyou jixie, 2022 In shale gas fracturing operation,the high-pressure manifold on the ground is generally connected by union with reliable seal and convenient disassembly.During operation,the high-pressure union vibrates violently and is seriously affected by external ...
Wang Yanran +3 more
doaj
Love, Plural Subjects & Normative Constraint
Phenomenology and Mind, 2016 Andrea Westlund’s account of love involves lovers becoming Plural Subjects mirroring Margaret Gilbert’s Plural Subject Theory. However, while for Gilbert the creation of a plural will involves individuals jointly committing to pool their wills and this ...
Joseph Kisolo-Ssonko
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source