Results 181 to 190 of about 847,240 (265)

Outcomes and Challenges of Allograft Reconstruction for Distal Tibial Tumors: A Retrospective Case Series. [PDF]

Cureus
W Md Yusof WY, Radhakrishnan S, Js A, Azid A.   +3 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Corrigendum to 'Establishment and characterization of an inflammatory cartilaginous organoids model for organoid transplantation study' [J Orthop Transl 52, May 2025, Pages 376-386]. [PDF]

J Orthop Translat
Zhang Y, Fang Q, Peng Y, Liu H, Tang J, Ma R, Wang W.   +6 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Case Report: Erdheim-Chester disease with liver involvement successfully treated with trametinib. [PDF]

Front Oncol
Chang L, Shen KN, Luo YP, Cao XX.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Book Reviews

Scottish Studies, 1964
J. Butt J. Dow
doaj  

Immune-mediated multisystem injury associated with monoclonal gammopathy of clinical significance: a case report. [PDF]

Front Immunol
Jin X, Duan X, Zhang R, Sun Y, Qian M, Li X, Ma D, Li X, Zhang X, Shen M, Zeng X, Xu N, Zhuang J.   +12 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source