Results 201 to 210 of about 847,240 (265)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Floating knees: variables affecting bone union and functional outcomes: a retrospective study of 72 cases. [PDF]

SICOT J
Salese Y, Cotte M, Druel T, Rongieras F, Bertani A, Viste A, Boyer B.   +6 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Efficacy and safety of MIPO versus ORIF in distal tibial fractures: a systematic review and meta-analysis. [PDF]

J Orthop Traumatol
Hassaan AM, Hassan AA, Abdelkhalik WS, Saad AM, Hosny AS, Elfeky BAEH, Mandour I, Ragheb MG, Elsayyad MAEA, Khalafalla MA, Imam MA.   +10 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Relative age effects in Rugby union and Rugby league: a systematic review and meta-analysis. [PDF]

Front Sports Act Living
Brustio PR, Cobley S, Ungureanu AN, McAuley ABT, Lupo C, Boccia G, Till K, Kelly AL.   +7 more
europepmc   +1 more source

Association Between Long-Term ACEI/ARB Use and Postoperative Pain in Hypertensive Patients: A Retrospective Cohort Study and Genetic Validation [Response to Letter]. [PDF]

J Pain Res
Li X, Che L, Shen L.
europepmc   +1 more source

Labor Unions, Union Density and the Union Wage Premium

, 2013
Hugo de Almeida Vilares, Pedro Portugal
openaire   +1 more source