Results 111 to 120 of about 675,154 (313)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
How Bad is Globalization for Labour Standards in the North? [PDF]
We analyse a world consisting of "the North" and "the South" where labour standards in the North are set by trade unions. Standards set by unions tend to increase output and welfare.
Alejandro DONADO, Klaus WALDE
core
Credit Union Capital, Insolvency, and Mergers Before and After Share Insurance [PDF]
, 2020 From their beginnings in 1908, U.S. credit unions have grown into a trillion-dollar industry with more than 100 million members. Despite many similarities, credit unions have always differed fundamentally from banks.
WILCOX, James A
core
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
South African Trade Unions: an Overview for 1995 to 2005 [PDF]
Trade unions played an important role in South Africa’s transition from apartheid in 1994 and continue to play a very public role in the South African economy. Trade unions are found to have had an increasingly positive effect on members’ wages, although
Janca Steenkamp, Paula Armstrong
core
Comment on: Medicaid changes under the Affordable Care Act [PDF]
, 2011 [Excerpt] These comments on the proposed regulations on the eligibility changes to Medicaid under the Affordable Care Act are submitted on behalf of the American Federation of Labor and Congress of Industrial Organizations ( AFL-CIO ) and its 57 ...
Feldman, Karin S.
core +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
O sindicalismo deixou a crise para trás?: um novo ciclo de greves na década de 2000
Caderno CRHO objetivo deste texto é retomar, de modo preliminar e indicativo, o debate sobre a crise ou o declínio histórico do movimento sindical. A questão que queremos levantar é a seguinte: a atividade sindical, na década de 2000, é um indicativo de que o ...
Armando Boito Jr., Paula Marcelino
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source