Results 171 to 180 of about 925,289 (363)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Banks vs. credit unions; dynamic competition in local markets [PDF]

open access: yes
One interesting aspect of the financial services industry is that for-profit institutions such as commercial banks compete directly with not-for-profit financial intermediaries such as credit unions.
Frank A. Schmid, William R. Emmons
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Unione Europea

open access: yes, 2011
Ricostruzione del processo di integrazione europea nel periodo 2014-2018: Commissione Juncker; La questione migratoria; la Brexit; Le istituzioni UE e le possibili riforme; Unione Economica e Monetaria (UEM) e Unione Bancaria; Politica estera, di vicinato e commerciale; I difficili rapporti tra Varsavia e ...
openaire   +3 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Consanguinity and adverse fetal outcomes- a population-based cohort study from a multiethnic population in the Middle East. [PDF]

open access: yesBMC Pregnancy Childbirth
Thomas J   +8 more
europepmc   +1 more source

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