Results 61 to 70 of about 163,505 (257)
Avocat en droit social : militer et défendre ?
While much research has focused on the legal profession in recent years, few have focused on the professional day-to-day lives of lawyers and relationships with their clients.
Jean-Philippe Tonneau
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Moral priority as a ‘‘formula for victory” in the works of Vadim Shefner
Vadim Shefner's fantastic prose serves as material for the article. The main term is considered the formula of victory, that is, the way in which the heroes achieve the desired result.
Oksana N. Almazova
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Examining the relationships between education, coresidential unions, and the fertility gap by simulating the reproductive life courses of Dutch women [PDF]
BACKGROUND: Couples in Europe have fewer children than they intend to, resulting in a gap between intended family size and completed fertility. This is partly because first-pregnancy attempts are postponed to older reproductive ages, when giving birth is
Rolf Granholm +2 more
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CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A modern child from birth becomes a consumer of a variety of information coming from all sorts of sources. That is why children today are the most unprotected, unprepared for the use of various kinds of information.
Gulbanu Т. Abitova
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Administrator's Bulletin, 2013 Kansas Department of Credit Unions Newsletter, 2014
In 2006, this publication changed its name to the KDCU Newsletter This internet resource contains publications issued throughout the year.Newsletter for the Kansas Department of Credit Unions covering issues of concern to credit unions in ...
Kansas. State Department of Credit Unions
core +2 more sources

