Results 71 to 80 of about 163,505 (257)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

FOR WHOM INTERNET MAY BE DANGEROUS

open access: yesІнформаційні технології і засоби навчання, 2010
Today in Ukraine as in the whole world the global network Internet is becoming as an integral part of the modern man life. Internet contains great the potential of information and education but simultaneous contains some risks especial for children ...
Lesia A. Ditkovska
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

INFORMATIZATION OF EDUCATION AND PROBLEMS OF IMPLANTATION OF PEDAGOGICAL SOFTWARE IN THE EDUCATIONAL PROCESS

open access: yesІнформаційні технології і засоби навчання, 2010
In the article the level of informatization of education in Ukraine, teachers equipment with domestic pedagogical software are analyzed, the problems concerning the implantation of electronic resources into the educational process which arise to teachers
Viktoriia P. Vember
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Certain Aspects of Copyright Protection in the Republic of Belarus / Отдельные аспекты защиты авторского права в Республике Беларусь

open access: yesBeneficium, 2019
In the course of human intelligence development, there is an increase in the volume of intellectual property objects and, accordingly, the need to protect these relations within the framework of the law.
Svyatoslav O. Khatsko / Святослав О. Хатько
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

South African Trade Unions: an Overview for 1995 to 2005 [PDF]

open access: yes
Trade unions played an important role in South Africa’s transition from apartheid in 1994 and continue to play a very public role in the South African economy. Trade unions are found to have had an increasingly positive effect on members’ wages, although
Janca Steenkamp, Paula Armstrong
core  

Kansas Department of Credit Unions Bulletin, 2022

open access: yes, 2022
This internet resource contains bulletins issued throughout the year.Credit Union Statistics -- NCUA 2022 Supervisory Priorities -- Human Trafficking -- Automated Cybersecurity Evaluation Toolbox -- Boards of Directors -- Supervisory Committees -- Credit
Kansas. State Department of Credit Unions
core  

Age-heterogamous partnerships: Prevalence and partner differences by marital status and gender composition [PDF]

open access: yesDemographic Research
OBJECTIVE: We examine age heterogamy in the United States and its associations with other partnership characteristics following the nationwide legalization of same-sex marriage in 2015.
Tony Silva, Christine Percheski
doaj   +1 more source

Home - About - Disclaimer - Privacy