Results 111 to 120 of about 3,278,971 (302)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
EXPONENCIAL DECAY FOR THE SEMILINEAR WAVE EQUATION WITH POTENTIAL AND LOCAL DISTRIBUTED DAMIPING
In this notes we shall study the exponential decay for the semilinear wave equation with potential and locally distributed damping, using the unique continuation principle, result studied by Ruíz [9] applied to problems of asymptotic behavior by Zuazua ...
Alfonso Pérez Salvatierra +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A New Method for the Exact Controllability of Linear Parabolic Equations
This work solves the exact controllability to zero in the final time for a linear parabolic problem when the control only acts in a part of the spatial domain. Specifically, it is proved, by compactness arguments, the existence of a partially distributed
Inmaculada Gayte Delgado +1 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
EXPONENTIAL DECAY OF WAVE EQUATION WITH A VISCOELASTIC BOUNDARY CONDITION AND SOURCE TERM
In this paper we are concerned with the stability of solutions for the wave equation with a viscoelastic Boundary condition and source term by using the potential well method, the multiplier technique and unique continuation theorem for the wave equation
Víctor Emilio Carrera Barrantes +3 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Unique integrability of continuous 𝑘-plane fields [PDF]
It is shown that unique integrability of a continuous k -plane field is a generic property for plane field satisfying a "topological bracket condition".
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Unique continuation principle for high order equations of Korteweg-de Vries type
In this article we consider the problem of unique continuation for high-order equations of Korteweg-de Vries type which include the kdV hierarchy.
Pedro Isaza
doaj

