Results 121 to 130 of about 3,278,971 (302)

Approximate controllability of the coupled degenerate system with two boundary controls

open access: yesBoundary Value Problems, 2017
In this paper, we investigate the approximate controllability of the coupled system with boundary degeneracy. The control functions act on the degenerate boundary. We prove the Carleman estimate and the unique continuation of the adjoint system.
Runmei Du
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Unique continuation of positive solutions for doubly degenerate quasilinear elliptic equations

open access: yesElectronic Journal of Differential Equations, 2017
We consider quasilinear elliptic equations that are degenerate in two ways. One kind of degeneracy is due to the particular structure of the given vector fields.
Giuseppe Di Fazio   +2 more
doaj  

Beyond the classical strong maximum principle: Sign-changing forcing term and flat solutions

open access: yesAdvances in Nonlinear Analysis
We show that the classical strong maximum principle, concerning positive supersolutions of linear elliptic equations vanishing on the boundary of the domain can be extended, under suitable conditions, to the case in which the forcing term is sign ...
Díaz Jesús Ildefonso   +1 more
doaj   +1 more source

THE NON LINEAR TRANSMISSION PROBLEM WITH TIME DEPENDENT COEFFICIENTS

open access: yesPesquimat, 2014
In this paper we consider the nonlinear transmission problem for the wave equation with time dependent coefficients and linear internal damping. We prove global existence and exponential decay of solution.
Jaime Edilberto Muñoz Rivera   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Continuous dependence of solutions for indefinite semilinear elliptic problems

open access: yesElectronic Journal of Differential Equations, 2013
We consider the superlinear elliptic problem $$ -\Delta u + m(x)u = a(x)u^p $$ in a bounded smooth domain under Neumann boundary conditions, where $m \in L^{\sigma}(\Omega)$, $\sigma\geq N/2$ and $a\in C(\overline{\Omega})$ is a sign changing ...
Elves A. B. Silva, Maxwell L. Silva
doaj  

THE TRANSMISSION PROBLEM WITH TIME DEPENDENT COEFFICIENTS WITH NONLINEAR INTERNAL DAMPING

open access: yesPesquimat, 2014
In this paper we consider the nonlinear transmission problem for the wave equation with time dependent coefficients and nonlinear internal damping. We prove global existence and study decay properties of the solutions. The result is achieved by using the
Eugenio Cabanillas Lapa   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy