Results 151 to 160 of about 250,996 (306)
Electronic Journal of Differential Equations, 2003 We prove existence and uniqueness of entropy solutions for the Cauchy problem of weakly coupled systems of nonlinear degenerate parabolic equations. We prove existence of an entropy solution by demonstrating that the Engquist-Osher finite difference ...
Helge Holden +2 more
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Electronic Journal of Differential Equations, 2006 We provide conditions for the existence and uniqueness of positive solutions to the quasilinear elliptic system $$displaylines{ -Delta _{p}u=f(x,u,v) cr -Delta _{q}v=g(x,u,v) }$$ with Dirichlet boundary conditions on a bounded domain $Omega
Dimitrios A. Kandilakis +1 more
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
The global inverse fractional conductivity problem. [PDF]
Calc Var Partial Differ EquCovi G, Railo J, Zimmermann P.
europepmc +1 more source
A unique journal by a unique editor in chief
Computer-Aided Civil and Infrastructure Engineering, 2020 openaire +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Indeterminacy in a forward-looking regime-switching model [PDF]
This paper is about the properties of Markov-switching rational expectations (MSRE) models. We discuss possible solution concepts for MSRE models, distinguishing between stationary and bounded equilibria.
Roger E.A. Farmer +2 more
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