Results 131 to 140 of about 273,864 (308)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Unicidad del equilibrio de Nash-Cournot con correspondencias de mejor respuesta contractivas [PDF]
In this work we obtain new conditions to uniqueness of Nash equilibrium in the Cournot oligopoly model. These conditions assure that the reaction functions are contractions and they are not reduced to the obtained ones by Rosen, inasmuch as they do not ...
Edgar Carrera, Elvio Accinelli
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Uniqueness in Determining Polygonal Periodic Structures
, 2007 We consider the inverse problem of recovering a two-dimensional perfectly reflecting diffraction grating from scattered waves measured above the structure.
Elschner, Johannes +3 more
core +1 more source
MathematicsIn this paper, we present sufficient conditions for Hyers-Ulam-Rassias stability of nonlinear implicit higher-order Volterra-type integrodifferential equations from above on unbounded time scales.
Andrejs Reinfelds, Shraddha Christian
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Uniqueness and non-uniqueness of semigroups generated by singular diffusion operators
, 1999 Eberle A. Uniqueness and non-uniqueness of semigroups generated by singular diffusion operators. Lecture notes in mathematics ; 1718.
Eberle, Andreas
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source