Results 161 to 170 of about 2,815,771 (370)
In this article, using the sub-supersolution method and Rabinowitz-type global bifurcation theory, we prove some results on existence, uniqueness and multiplicity of positive solutions for some singular nonlocal elliptic problems.
Baoqiang Yan, Qianqian Ren
doaj
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
On the uniqueness of limit cycles for Liénard equations: the legacy of G. Sansone
We give an account of the results about limit cycle’s uniqueness for Liénard equations, starting from Levinson-Smith’s one to the most recent ones. We present a new uniqueness theorem in the line of Sansone-Massera’s geometrical approach.
Marco Sabatini, Gabriele Villari
doaj
Svalbard in International Politics 1871-1925: The Solution of a Unique International Problem [PDF]
Oscar J. Falnes, Trygve Mathisen
openalex +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
“Essai d'une classification des races humaines, basée uniquement sur les caractères physiques. Par M. J. Deniker” [PDF]
O. T. Mason
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
In this paper, we consider the second initial boundary value problem for strongly general Schrodinger systems in both the finite and the infinite cylinders $Q_T ...
Nguyen Manh Hung, Nguyen Thi Kim Son
doaj