Results 161 to 170 of about 3,546,472 (360)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Global in time well-posedness of a three-dimensional periodic regularized Boussinesq system

open access: yesDemonstratio Mathematica
Global in time weak solution to a regularized periodic three-dimensional Boussinesq system is proved to exist in energy spaces. This solution depends continuously on the initial data. In particular, it is unique.
Almutairi Shahah
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Solutions of fourth-order partial differential equations in a noise removal model

open access: yesElectronic Journal of Differential Equations, 2007
In this paper, we discuss the existence and uniqueness of weak solutions for a fourth-order partial differential equation stemmed from image processing for noise removal. We also present some numerical tests for high order filters.
Yuanyuan Ke, Zhengan Yao, Qiang Liu
doaj  

Levodopa modulates semantic fluency and uniqueness in non‐demented patients with progressive supranuclear palsy

open access: yesBrain and Behavior
Introduction Semantic fluency is the ability to name items from a given category within a limited time, which relies on semantic knowledge, working memory, and executive function.
Jinghong Ma   +4 more
doaj   +1 more source

On a Unique Feature of Statistics [PDF]

open access: bronze, 1949
George W. Snedecor
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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