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Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Deference and Uniqueness [PDF]
Deference principles are principles that describe when, and to what extent, it’s rational to defer to others. Recently, some authors have used such principles to argue for Evidential Uniqueness, the claim that for every batch of evidence, there’s a ...
Meacham, Christopher
core
Canonical Polyadic (also known as Candecomp/Parafac) Decomposition (CPD) of a higher-order tensor is decomposition in a minimal number of rank-1 tensors. In Part I, we gave an overview of existing results concerning uniqueness and presented new, relaxed,
De Lathauwer, Lieven, Domanov, Ignat
core +1 more source
Topological freeness for $C^*$-correspondences [PDF]
We study conditions that ensure uniqueness theorems of Cuntz-Krieger type for relative Cuntz-Pimsner algebras $\mathcal{O}(J,X)$ associated to a $C^*$-correspondence $X$ over a $C^*$-algebra $A$.
Carlsen, T. M.+2 more
core +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In this paper, we discuss the existence and uniqueness of boundary value problems for sequential ψ-Hilfer fractional pantograph differential equations with mixed nonlocal boundary conditions.
Karim Guida+3 more
doaj +1 more source
Uniqueness of Simultaneity [PDF]
We consider the problem of uniqueness of certain simultaneity structures in flat spacetime. Absolute simultaneity is specified to be a non-trivial equivalence relation which is invariant under the automorphism group Aut of spacetime.
Giulini, Domenico
core +1 more source
On uniqueness of mild solutions for dissipative stochastic evolution equations
In the semigroup approach to stochastic evolution equations, the fundamental issue of uniqueness of mild solutions is often "reduced" to the much easier problem of proving uniqueness for strong solutions. This reduction is usually carried out in a formal
Marinelli, Carlo, Röckner, Michael
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source