Results 71 to 80 of about 273,864 (308)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A New Sufficient Condition for Uniqueness in Continuous Games [PDF]

open access: yes
Consider the class of games in which each player chooses a strategy from a connected subset of the real line. Many oligopoly models fall into this class.
Seamus Hogan
core  

Transference and Preservation of Uniqueness [PDF]

open access: yes, 2019
Motivated by the notion of a set of uniqueness in a locally compact group G, we introduce and study ideals of uniqueness in the Fourier algebra A(G) of G, and their accompanying operator version, masa-bimodules of uniqueness.
Todorov, Ivan G.   +6 more
core   +1 more source

Challenges at different stages of an iris based biometric system [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2012
Iris recognition has been used for authentication for the past few years and is capable of positive/negative authenticationof an individual without any physical contact or intervention.
Sunil Kumar Singla, Parul Sethi
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Existence and Uniqueness of a Fixed-Point for Local Contractions [PDF]

open access: yes
This paper proves the existence and uniqueness of a fixed-point for local contractions without assuming the family of contraction coefficients to be uniformly bounded away from 1.
Vailakis, Yiannis   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Fourier uniqueness and non-uniqueness pairs

open access: yes, 2023
Motivated by recent works by Radchenko and Viazovska and by Ramos and Sousa, we find sufficient conditions for a pair of discrete subsets of the real line to be a uniqueness or a non-uniqueness pair for the Fourier transform.
Kulikov, Aleksei   +2 more
core  

On the asymptotic uniqueness of bargaining equilibria [PDF]

open access: yes
The paper studies the model of multilateral bargaining over the alternatives representedby points in the mâdimensional Euclidean space. Proposers are chosen randomly and the acceptance of a proposal requires the unanimous approval of it by all the ...
Predtetchinski Arkadi
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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