Results 91 to 100 of about 200,235 (314)

Positive solutions for a class of fractional boundary value problems

open access: yesNonlinear Analysis, 2016
In this work, by virtue of the Krasnoselskii–Zabreiko fixed point theorem, we investigate the existence of positive solutions for a class of fractional boundary value problems under some appropriate conditions concerning the first eigenvalue of the ...
Jiafa Xu, Zhongli Wei
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Existence of solutions to Burgers equations in a non-parabolic domain

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we study the semilinear Burgers equation with time variable coefficients, subject to boundary condition in a non-parabolic domain. Some assumptions on the boundary of the domain and on the coefficients of the equation will be imposed.
Yassine Benia, Boubaker-Khaled Sadallah
doaj  

On uniqueness and stability of symmetric equilibria in differentiable symmetric games [PDF]

open access: yes
Higher-dimensional symmetric games become of more and more importance for applied micro- and macroeconomic research. Standard approaches to uniqueness of equilibria have the drawback that they are restrictive or not easy to evaluate analytically. In this
Andreas Hefti
core  

LARGE SOLUTIONS FOR YAMABE AND SIMILAR PROBLEMS ON DOMAINS IN RIEMANNIAN MANIFOLDS

open access: yes, 2011
We present a unified approach to study large positive solutions (i.e., u(x) -> infinity as x -> partial derivative Omega) of the equation Delta u + hu - k psi(u) = -f in an arbitrary domain Omega.
Martin Dindoš, Dindos, Martin; id_orcid
core   +1 more source

Uniqueness and conformity [PDF]

open access: yesQJM: An International Journal of Medicine, 2003
If you observe medical consultations closely, you will nearly always observe some kind of struggle going on between medical and lay styles of conversation. Patients mostly display a style that is best described as a narrative one, while doctors pursue one that is more normative. (The distinction is my own, but it closely follows the psychologist Jerome
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Weak solutions for quasilinear degenerate parabolic systems

open access: yesElectronic Journal of Differential Equations, 2006
This paper concerns the initial Dirichlet boundary-value problem for a class of quasilinear degenerate parabolic systems. Due to the degeneracies, the problem does not have classical solutions in general.
Zheng'an Yao, Wenshu Zhou
doaj  

Solution of a boundary value problem for a third-order inhomogeneous equation with multiple characteristics with the construction of the Green’s function

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In the paper the second boundary value problem in a rectangular domain for an inhomogeneous third-order partial differential equation with multiple characteristics with constant coefficients was considered.
Ю.П. Апаков, Р.А. Умаров
doaj   +1 more source

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