Results 81 to 90 of about 200,235 (314)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Uniqueness of solutions to singular p-Laplacian equations with subcritical nonlinearity
Advances in Nonlinear Analysis, 2017 We present a geometric approach to the study of quasilinear elliptic p-Laplacian problems on a ball in ℝn${\mathbb{R}^{n}}$ using techniques from dynamical systems.
Maultsby Bevin
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Generalization on uniqueness of non-linear dierential polynomials sharing 1-points
, 2017 [[abstract]]In this paper, we generalize two theorems on the uniqueness of non-linear differential polynomials sharing 1-points, which improves a result of Indrajit Lahiri and Pulak ...
Harina P. Waghamore, Husna V.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Independence, Heterogeneity and Uniqueness in Interaction Games [PDF]
This paper shows that incomplete information and sufficient heterogeneity of players can ensure uniqueness in interaction games. In contrast to recent work on uniqueness in interaction games, we do not require strategic complementarity.
Robin Mason, Akos Valentinyi
core
Uniqueness implies existence for (n,p) boundary value problems
, 2010 The uniqueness of solutions of certain boundary value problems implies their existence for the nth order nonlinear ordinary differential equation y(n)=f(x,y,y',y'',....,y(n-1)) This existence is established by using shooting methods and yields results ...
錢傳仁; Chyan, Chuan-jen; Henderson, J.
core +1 more source
Uniqueness for dissipative Schrödinger--Poisson systems [PDF]
, 2005 The paper is devoted to the dissipative Schroedinger-Poisson system. We indicate conditions in terms of the Schroedinger-Poisson data which guarantee the uniqueness of the solution. Moreover, it is shown that if the system is sufficiently small shrunken,
Neidhardt, Hagen +3 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Global solutions of a model of phase transitions for dissipative thermoviscoelastic materials
Electronic Journal of Differential Equations, 2013 We analyze a highly nonlinear system of partial differential equations that may be seen as a model for solidification or melting of certain viscoelastic materials subject to thermal effects; under the assumption that solid parts of the material may ...
Welington Vieira Assuncao +1 more
doaj