Results 51 to 60 of about 47,857 (276)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

On the group ring.

open access: yes, 1963
In this thesis we study the group ring of an arbitrary group over an associative ring with unit element. Classically the group ring studied was that of a finite group over a field, and with the introduction of group characters a number of theorems on ...
Connell, Ian. G., Ian G. Connell
core   +1 more source

On Weakly 2-Invo Clean Rings With Some Properties in Graph Theory

open access: yesInternational Journal of Mathematics and Mathematical Sciences
The concept of a weakly two-involution clean ring is presented; it is a generalization of two-involution clean ring, which allows the addition of more elements to a ring, which will be observed in its graph theoretic representation.
Salim Ghadeer Salim   +2 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Deep neural network-based automatic metasurface design with a wide frequency range

open access: yesScientific Reports, 2021
Beyond the scope of conventional metasurface, which necessitates plenty of computational resources and time, an inverse design approach using machine learning algorithms promises an effective way for metasurface design.
Fardin Ghorbani   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

First-Principles Study of the Structural Evolution of Microcline Under High Pressure

open access: yesCrystals
Microcline is an important rock-forming mineral in the Earth’s crust, and characterizing its structural behavior under compression is essential for understanding the high-pressure response of feldspar minerals under geological conditions.
Baoyun Wang, Meisu Xiang
doaj   +1 more source

Crystal structure and optical spectroscopic analyses of (E)-3-(1H-indol-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one hemihydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
The asymmetric unit of the title compound, 2C17H12N2O3·H2O comprises two molecules of (E)-3-(1H-indol-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one and a water molecule. The main molecule adopts an s-cis configuration with respect to the C=O and C=C bonds.
Muhamad Fikri Zaini   +3 more
doaj   +1 more source

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