Results 61 to 70 of about 5,733,832 (305)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Unit Root Testing with Unstable Volatility [PDF]

Journal of Time Series Analysis, 2017
Unit root test statistics may not have the usual asymptotic properties when the variance of innovations is unstable. In particular, persistent changes in volatility can cause the size to differ from the nominal level. We propose a class of modified unit root test statistics that are robust to the presence of unstable volatility.
openaire   +3 more sources

Bootstrap Unit‐Root Tests: Comparison and Extensions [PDF]

Journal of Time Series Analysis, 2008
Abstract.  In this article, we study and compare the properties of several bootstrap unit‐root tests recently proposed in the literature. The tests are Dickey–Fuller (DF) or Augmented DF, based either on residuals from an autoregression and the use of the block bootstrap or on first‐differenced data and the use of the stationary bootstrap or sieve ...
Palm, F.C., Smeekes, S., Urbain, J.R.Y.J.   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Panel Unit Root Tests by Combining Dependent 𝑃 Values: A Comparative Study

Journal of Probability and Statistics, 2011
We conduct a systematic comparison of the performance of four commonly used 𝑃 value combination methods applied to panel unit root tests: the original Fisher test, the modified inverse normal method, Simes test, and the modified truncated product method (
Xuguang Sheng, Jingyun Yang
doaj   +1 more source

Unit Root Tests for ESTAR Models

Journal of Statistical Theory and Practice, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Puspaningrum, Heni, Lin, Yan-Xia, Gulati, Chandra   +2 more
openaire   +4 more sources

Markov Regime-Switching and Unit Root Tests [PDF]

International Finance Discussion Papers, 2000
We investigate the power and size performance of unit root tests when the true data generating process undergoes Markov regime-switching. All tests, including those robust to a single break in trend growth rate, have very low power against a process with a Markov-switching trend growth rate as in Lam (1990).
Charles R. Nelson, Jeremy Piger, Eric W. Zivot   +2 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Examination of inflation convergence using fourier unit root tests: OECD countries

Ekoist Journal of Econometrics and Statistics
This study examines the validity of the inflation convergence hypothesis in OECD countries, which include both developed and developing countries. Using monthly data for the period 1995:01 to 2023:01, the results of the analysis were obtained using the ...
Süreyya İmre Bıyıklı
doaj   +1 more source