Results 101 to 110 of about 15,412,407 (389)

Prevalence of Tick-Borne Pathogens in Ixodes scapularis in a Rural New Jersey County

open access: yesEmerging Infectious Diseases, 1998
To assess the potential risk for other tick-borne diseases, we collected 100 adult Ixodes scapularis in Hunterdon County, a rapidly developing rural county in Lyme disease–endemic western New Jersey.
Shobha Varde, John Beckley, Ira Schwartz
doaj   +1 more source

Invasive methicillin-resistant Staphylococcus aureus infections in the United States.

open access: yesJournal of the American Medical Association (JAMA), 2007
CONTEXT As the epidemiology of infections with methicillin-resistant Staphylococcus aureus (MRSA) changes, accurate information on the scope and magnitude of MRSA infections in the US population is needed.
R. M. Klevens   +15 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Women’s Employment During the Recovery [PDF]

open access: yes, 2011
[Excerpt] In 2010, women represented 46.7 percent of the United States labor force, a slightly larger share than at the start of the recession in 2007. Overall 71.9 million women were employed or looking for work, representing 58.6 percent of all women ...
United States Department of Labor
core   +1 more source

Ventilator-Associated Pneumonia or Not? Contemporary Diagnosis

open access: yesEmerging Infectious Diseases, 2001
Ventilator-associated pneumonia (VAP) is pneumonia in patients who have been on mechanical ventilation for >48 hours. VAP is most accurately diagnosed by quantitative culture and microscopic examination of lower respiratory tract secretions, which are ...
C. Glen Mayhall
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Economic Impact of Antimicrobial Resistance

open access: yesEmerging Infectious Diseases, 2001
One reason antimicrobial-drug resistance is of concern is its economic impact, which affects physicians, patients, health-care administrators, pharmaceutical producers, and the public.
John E. McGowan
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Rickettsial Pathogens and Their Arthropod Vectors

open access: yesEmerging Infectious Diseases, 1998
Rickettsial diseases, important causes of illness and death worldwide, exist primarily in endemic and enzootic foci that occasionally give rise to sporadic or seasonal outbreaks.
Abdu F. Azad, Charles B. Beard
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

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