Results 51 to 60 of about 5,966,718 (341)
A Moment in History Relevant to the Modern Era
, 2017 April 6, 1917 is a date that deserves great recognition and remembrance in the United States. On that day, the United States chose to enter a war that it had previously so ardently tried to avoid.
Katzung Hokanson, Brandon R.
core
Diversity and Transformation: African Americans and African Immigration to the United States [PDF]
, 2005 Successive generations of African immigration have continuously transformed the African American community and the sociopolitical climate of the United States.Though the history of African immigration to the United States has at times been a turbulent ...
Salih Omar Eissa
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
White Conceptions of Racial Hierarchy: Temporary versus Permanent Preferences [PDF]
, 2006 Ideas of race, racial identity, and racial categorization, reflect the inconsistent, context-specific and fluctuating nature of racial meaning (Nagel, 1986; Forbes, 1990; Davis, 1991; Nagel, 1994; Haney-Lopez, 1995; Ignatiev, 1995; Kibria, 1996,1998 ...
Gayles, Jonathan, Tobin, Sarah
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gun Law History in the United States and Second Amendment Rights [PDF]
, 2017 The plethora of early gun laws herein described establish their prolific existence, but also validate the argument that gun rules and gun rights are by no means at odds.
Spitzer, Robert J.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Surveillance of Physical Activity and Sedentary Behavior Among Youth and Adults in the United States: History and Opportunities. [PDF]
J Phys Act Health, 2021 Omura JD +6 more
europepmc +1 more source