Results 71 to 80 of about 5,966,718 (341)

[Review of] James A. Clifton. The Prairie People: Continuity and Change in Potawatomi Indian Culture, 1665-1965 [PDF]

open access: yes, 1979
Until very recently, Indian history existed in the doldrums of guilt and ethnocentric misunderstanding. Since Indians were preeminently the great American obstacle to the inexorable process of United States expansion and progress, they have been ...
Morrison, Kenneth M.
core   +1 more source

Population Disease Prevention Under Sovereign and Disciplinary Pandemic Authority [PDF]

open access: yes, 2020
The history of collective action aimed at disease prevention amongst populations is replete with complexity in the operation of political power which has transformed in its deployment over time.
Porter, Dorothy
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Transcriptome analysis illuminates the nature of the intracellular interaction in a vertebrate-algal symbiosis

open access: yeseLife, 2017
During embryonic development, cells of the green alga Oophila amblystomatis enter cells of the salamander Ambystoma maculatum forming an endosymbiosis.
John A Burns   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Principles, Pragmatism, and Politics: The Evolution of Washington State’s Sentencing Guidelines [PDF]

open access: yes, 2013
Although the U.S. Federal Sentencing Guidelines have received much attention (and criticism), we do well to remember that the United States is a federal system, and that each of the fifty states has its own sentencing rules and procedures. Today, roughly
Stith, Kate
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

“C-ing” the River: from Companionship to Control to…Catastrophe or Compromise?

open access: yesOpen Rivers, 2017
What humanity needs to do in the coming decades is back off. In our quest for comfort, consumption, stability, and security in our lives, we have done too much with the earth.
Stevan Harrell
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The role of flourishing in the STEM trajectories of emerging adults

open access: yesFrontiers in Education
We focus on the use of flourishing as a new measure in studies of pathways in STEM (science, technology, engineering, and mathematical) fields. While the concept of flourishing is promising, the concept may need careful interrogation to ensure it takes ...
Karen Hammerness   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy