Results 81 to 90 of about 4,135,250 (349)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
A Segunda Escravidão e a Primeira República Americana
AlmanackResumo Este artigo reescreve a história dos Estados Unidos antes da Guerra Civil, tomando por base quatro fases de sua história financeira. Essas fases mapeiam os ciclos cambiantes de boom and bust, movidos pelos anseios dos empresários em expandir a ...
Edward E. Baptist
doaj +1 more source
Laird W Bergad. The Comparative Histories of Slavery in Brazil, Cuba, and the United States. [New Approaches to the Americas.]Cambridge University Press, Cambridge [etc.] 2007. xiv, 314 pp. Ill. £45.00; $80.00. (Paper: £15.99; $22.99) [PDF]
, 2010 Dick Geary
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
New York and the politics of central banks, 1781 to the Federal Reserve Act [PDF]
The paper provides a brief history of central banking institutions in the United States. Specifically, the authors highlight the role of New York banking interests in the legislations affecting the creation or expiration of central banking institutions ...
Ellis W. Tallman, Jon R. Moen
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A New Standard for Governance: Reflections on Worker Representation in the United States [PDF]
, 2019 The contemporary state of corporate law in the United States is one that is skewed toward the archaic principle of shareholder primacy. This narrow conception of corporate purpose has resulted in governance mechanisms that tend to overlook the many ...
Constain, Julian
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The Calm in the Storm: Women Leaders in Gulf Coast Recovery [PDF]
, 2006 Report outlining the importance of women in Gulf Coast Recovery actions.One year after Hurricanes Katrina and Rita, women stand at the forefront of constituencies who have taken up leadership for a fair and just recovery, drawing on a history of ...
Sarah Vaill
core