Results 181 to 190 of about 911,909 (305)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Evaluation of acid rain in urban areas of the United States of America and Mexico from 2003 to 2019. [PDF]

open access: yesEnviron Monit Assess
Jiménez Alcántara A   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Experienced and Anticipated Intersectional Violence and Psychological Distress Symptom Severity Among Black Transgender Women in the United States of America. [PDF]

open access: yesHealthcare (Basel)
Sherman ADF   +11 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Investigation of Cellular Mechanism through which Salmonella Enterica Serovar Enteritidis Induces Melanoma Cell Death

open access: yesEJC Skin Cancer
B. Kuran   +12 more
doaj   +1 more source

North America 1856

open access: yes
Covers Arizona and New Mexico. Relief shown by hachures. Also shows Indian tribe locations. "Surveyor Generals office, Santa Fe, September 30th 1855, Wm. Pelham, Surveyor General of New Mexico." At head of title: B.
United States. Surveyor General of New Mexico
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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