Results 51 to 60 of about 5,695 (289)

Avoiding communication through a multilevel LU factorization [PDF]

open access: yes, 2012
Due to the evolution of massively parallel computers towards deeper levels of parallelism and memory hierarchy, and due to the exponentially increasing ratio of the time required to transfer data, either through the memory hierarchy or between different ...
Khabou, Amal   +2 more
core  

On effective computation of fundamental units. I

open access: yes, 1982
The new method for efficient computation of the fundamental units of an algebraic number field developed by the authors in an earlier paper is considerably improved with respect to (Section 1) utilization to best advantage of the element of choice ...
Hans Zassenhaus, Michael Pohst
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The monotone-light factorization for n-categories via n-preorders [PDF]

open access: yes, 2023
Starting with a symmetric monoidal adjunction with certain properties, one derives another symmetric monoidal adjunction with the same properties between the respective categories of all V-categories.
Xarez, João J.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Research on Personalized Recommendation Algorithm Integrating Cross-Grained Sentiment and Rating Interaction Features

open access: yesIEEE Access
To investigate the impact of cross-grained sentiments on user feature representation and address the issue of data sparsity, this paper proposes a Personalized Recommendation Algorithm Integrating Cross-Grained Sentiment and Rating Interaction Features ...
Bing Li   +4 more
doaj   +1 more source

VB-MK-LMF: fusion of drugs, targets and interactions using variational Bayesian multiple kernel logistic matrix factorization

open access: yesBMC Bioinformatics, 2017
Background Computational fusion approaches to drug-target interaction (DTI) prediction, capable of utilizing multiple sources of background knowledge, were reported to achieve superior predictive performance in multiple studies. Other studies showed that
Bence Bolgár, Péter Antal
doaj   +1 more source

Parallel Sparse LU Factorization of Power Flow Jacobian using GPU

open access: yes, 2019
Parallelizing the LU factorization of sparse Jacobian matrices reduces the execution time of the power flow algorithm which aids in real time control of the power system.
Gnanavignesh, R   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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