Results 151 to 160 of about 1,872,952 (282)

P516: The Genetics Navigator: The development and usability testing of a new patient-facing digital health application to support clinical genetic testing

Genetics in Medicine Open
Marc Clausen, Stephanie Luca, Emma Reble, Rita Kodida, Saumeh Saeedi, Daena Hirjikaka, Lauren Chad, Gregory Costain, Hanna Faghfoury, Josh Silver, Serena Shastri-Estrada, Maureen Smith, Robin Hayeems, Yvonne Bombard   +13 more
doaj   +1 more source

The Kantian background of Uexküll's notions of time and space. [PDF]

Hist Philos Life Sci
Müller J.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bench Evaluation of Intraocular Pressure Control with Clinical Assessment of Anterior Chamber Stability of a Dual Peristaltic Phacoemulsification Device. [PDF]

Clin Ophthalmol
Berdahl J, Terveen D, Aboughaida A, Dyk DW, Yalamanchili S, Makari S, Thompson V.   +6 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Unity House News Winter 2013 [PDF]

, 2013
Connecticut College
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Persistent Neuroendocrine Function is Still Vegetative: A Reply to Berendes. [PDF]

Linacre Q
DeCock CA, Feikles CF, Thomas C, Donovan GK, Tornatore CS, Sulmasy DP.   +5 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Plasma CHI3L1 as a marker of cognitive and structural brain changes in radiologically isolated syndrome. [PDF]

BMJ Neurol Open
Schneider R, Brand-Arzamendi K, Lim TR, Lee LE, Guenette M, Hu Z, Colak E, Suthiphosuwan S, Bharatha A, Feinstein A, Oh J.   +10 more
europepmc   +1 more source