Results 251 to 260 of about 1,861,870 (345)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Correction to Pattern of extra-diaphragmatic respiratory muscle activity during exercise in patients with unilateral diaphragm dysfunction. [PDF]

Physiol Rep
europepmc   +1 more source

Ultrafast avalanche photodiode exceeding 100 GHz bandwidth. [PDF]

Nat Commun
Shi Y, Zou M, Li Z, Yu Y, Zhang X.
europepmc   +1 more source

A Distant Council, Nearby Problems. The Duke of Medinaceli, Naples, and the Unity of the Spanish Monarchy, 1696-1702

, 2018
David Martín Marcos
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

P555: Clinical utility returning of all types of medically relevant genomic sequencing findings: An observational study

Genetics in Medicine Open
Chloe Mighton, Rita Kodida, Salma Shickh, Marc Clausen, Emma Reble, Jordan Sam, Sonya Grewal, Seema Panchal, Melyssa Aronson, Susan Armel, Tracy Graham, Nicole Forster, Jose-Mario Capo-Chichi, Elena Greenfeld, Abdul Noor, Iris Cohn, Chantal Morel, Christine Elser, Andrea Eisen, June Carroll, Emily Glogowski, Kasmintan Schrader, Kelvin Chan, Kevin Thorpe, Jordan Lerner-Ellis, Raymond Kim, Yvonne Bombard   +26 more
doaj   +1 more source

Autonomous agents: Augmenting visual information with raw audio data. [PDF]

PLoS One
Solomon E.
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Facilitators and Barriers to the Implementation of Family Integrated Care in Ontario Level II Neonatal Intensive Care Units. [PDF]

Children (Basel)
Al Bizri A, Bueno M, Shah V, Bacchini F, Campbell DM, Benzies KM, O'Brien K.   +6 more
europepmc   +1 more source

The establishment of European unity. Summary of an address by Professor Walter Hallstein, President of the Commission of the European Economic Community, to Dutch students. The Hague, 2 April 1962 [PDF]

, 1962
Walter. Hallstein
openalex