Results 81 to 90 of about 1,861,870 (345)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Don\u27t Fall for the Lies Behind Trump\u27s Calls for Unity
, 2017 Each summer, more than half a million tourists come to Gettysburg, a battlefield in the most divisive conflict in American history. After marching around in the heat, thousands stop in at Mr. G’s for some of the best ice cream in town.
Hancock, Scott
core
Nested calcium dynamics support daily cell unity and diversity in the suprachiasmatic nuclei of free-behaving mice [PDF]
, 2022 Lama Hussein +3 more
openalex +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
John 17:6-19: exegesis case study [PDF]
, 1981 John 13-21. The article explores the place of the unity motif in Jn 17:6-19. After a brief survey of the scholarly consensus regarding the levels of composition and the cultural and religious milieu of the Fourth Gospel, the study analyses the structure
Buck, Erwin
core +1 more source
Bulletin of the World Health Organization, 2009 Recent increases in resources for achiev-ing the goal of universal access to HIV prevention, treatment, care and support have given renewed impetus to the longer-standing political commitment for achieving targets in sexual and repro-ductive health and rights.
Michel Sidibé, Kent Buse
openaire +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Why emerging leaders should focus on being good postdoctoral supervisors
FEBS Letters, EarlyView.Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski +5 more
wiley +1 more source