Results 101 to 110 of about 6,477,034 (245)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Alkalmazásfejlesztés Unity-ben
, 2018 Szakdolgozatomban egy háromdimenziós többjátékos bújócska játékos készítettem el, melyhez a Unity nevű játékmotort és a C# programozási nyelvet használtam fel.
Zöld, Krisztián
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Organization of African Unity the ad hoc Commission on the Algeria-Morocco Border Dispute
, 1964 Ad hoc Commission on the Algeria-Morocco Border Dispute, Khartoum, 26 September 1964It is a draft recommendation of the ad hoc Commission on the Algeria-Morocco Border Dispute which was set up by the Council of the Organization of African Unity during ...
Organization of African Unity
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Relations between the Economic Commission for Africa and the Organization of African Unity
, 1966 Council of Ministers, Seventh Ordinary Session, Addis Ababa, October-November 1966This report is organized with the aim of analyzing the principal provisions of the agreement between United Nations Economic Commission for Africa and the Organization of ...
Organization of African Unity
core +1 more source
Nipocalimab Phase 3 Dose Selection for Severe Hemolytic Disease of the Fetus and Newborn. [PDF]
J Clin PharmacolZhou J +8 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
New <i>para</i>-hydrogen cold neutron source at the Budapest Research Reactor: Monte Carlo simulations. [PDF]
J Appl CrystallogrShapiro D, Konik P, Akhyani M, Ioffe A.
europepmc +1 more source